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Polymers in regenerative medicine : biomedical applications from nano- to macro-structures

Manuel. Monleon Pradas Maria J Vicent

Hoboken, New Jersey : John Wiley & Sons 2015

Online access

  • Title:
    Polymers in regenerative medicine : biomedical applications from nano- to macro-structures
  • Author: Manuel. Monleon Pradas
  • Maria J Vicent
  • Subjects: Polymers; Nanomedicine; Electronic books
  • Contents: Polymers in Regenerative Medicine: Biomedical Applications from Nano- to Macro-Structures; Copyright; Contents; Preface; Contributors; Part A Methods for Synthetic Extracellular Matrices and Scaffolds; Chapter 1 Polymers as Materials for Tissue Engineering Scaffolds; 1.1 The Requirements Imposed by Application on Material Structures Intended as Tissue Engineering Scaffolds; 1.2 Composition and Function; 1.2.1 General Considerations; 1.2.2 Some Families of Polymers for Tissue Engineering Scaffolds; 1.2.3 Composite Scaffold Matrices; 1.3 Structure and Function; 1.3.1 General Considerations
    1.3.2 Structuring Polymer Matrices1.4 Properties of Scaffolds Relevant for Tissue Engineering Applications; 1.4.1 Porous Architecture; 1.4.2 Solid State Properties: Glass Transition, Crystallinity; 1.4.3 Mechanical and Structural Properties; 1.4.4 Swelling Properties; 1.4.5 Degradation Properties; 1.4.6 Diffusion and Permeation; 1.4.7 Surface Tension and Contact Angle; 1.4.8 Biological Properties; 1.5 Compound, Multicomponent Constructs; 1.5.1 Scaffold-Cum-Gel Constructs; 1.5.2 Scaffolds and Membranes Containing Microparticles; 1.5.3 Other Multicomponent Scaffold Constructs
    1.6 Questions Arising from Manipulation and Final Use1.6.1 Sterilization; 1.6.2 Cell Seeding, Cell Culture, Analysis; 1.6.3 In the Surgeon's Hands; Acknowledgments; References; Chapter 2 Natural-Based and Stimuli-Responsive Polymers for Tissue Engineering and Regenerative Medicine; 2.1 Introduction; 2.2 Natural Polymers and Their Application in TE & RM; 2.2.1 Polysaccharides; 2.2.2 Protein-Based Polymers; 2.2.3 Polyesters; 2.3 Natural Polymers in Stimuli-Responsive Systems; 2.3.1 pH-Sensitive Natural Polymers; 2.3.2 Temperature Sensitive Natural Polymers
    2.3.3 Natural Polymers Modified to Show Thermoresponsive Behavior-Modifying Responsive Polymers and Agents2.3.4 Light-Sensitive Polymers-Potential Use of Azobenzene/╬▒-Cyclodextrin Inclusion Complexes; 2.4 Conclusions; Acknowledgments; References; Chapter 3 Matrix Protein Interactions with Synthetic Surfaces; 3.1 Introduction; 3.2 Protein Adsorption; 3.2.1 Cell Adhesion Proteins; 3.2.2 Experimental Techniques to Follow Protein Adsorption; 3.2.3 Effect of Surface Properties on Protein Adsorption; 3.3 Cell Adhesion; 3.3.1 Experimental Techniques to Characterize Cell Adhesion
    3.3.2 Cell Adhesion at Cell-Material Interface3.4 Remodeling of the Adsorbed Proteins; 3.4.1 Protein Reorganization and Secretion at the Cell-Material Interface; 3.4.2 Proteolytic Remodeling at Cell-Materials Interface; Acknowledgments; References; Chapter 4 Focal Adhesion Kinase in Cell-Material Interactions; 4.1 Introduction; 4.2 Role of FAK in Cell Proliferation; 4.3 Role of FAK in Migratory and Mechanosensing Responses; 4.4 Role of FAK in the Generation of Adhesives Forces; 4.5 Influence of Material Surface Properties on FAK Signaling
    4.5.1 Effect of Mechanical Properties on FAK Signaling
    Biomedical applications of Polymers from Scaffolds toNanostructures The ability of polymers to span wide ranges of mechanicalproperties and morph into desired shapes makes them useful for avariety of applications, including scaffolds, self-assemblingmaterials, and nanomedicines. With an interdisciplinary list ofsubjects and contributors, this book overviews the biomedicalapplications of polymers and focuses on the aspect of regenerativemedicine. Chapters also cover fundamentals, theories, and tools forscientists to apply polymers in the following ways: Matrix protein interactions with synthe
    Description based upon print version of record.
  • Publisher: Hoboken, New Jersey : John Wiley & Sons
  • Creation Date: 2015
  • Physical Description: 1 online resource (424 p.).
  • Language: English
  • Identifier: ISBN1-118-90581-4;ISBN1-118-35668-3;ISBN1-118-35669-1
  • NZ MMS ID: 9913747825002931

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